Alzheimer’s Disease how to fight Naturally

A new study reports on the benefit of high dose Vitamin E in patients with mild to moderate Alzheimer’s Disease. Compared to placebo, patients taking Vitamin E had slower functional decline and needed less caregiver assistance.

Read more about this research below: A recent study published in the Journal of the American Medical Association reported on the benefits of vitamin E supplementation in mild to moderate Alzheimer’s disease. Researchers sought to determine if vitamin E, memantine (an ACE inhibitor), or both would slow progression of mild to moderate Alzheimer’s Disease (AD). The double-blind, placebo-controlled, randomized clinical trial involved 613 patients with mild to moderate AD. Participants were randomized to receive 2,000 international units (IU) of vitamin E, 20 milligrams of memantine, a combination of both, or a placebo daily. Average follow-up was 2.3 years. Patients were analyzed on their capability to perform daily living activities, memory and language, cognitive function, behavioral and psychological issues, and the time needing caregiver assistance. The data was measured and collected at the beginning of the study and every six months during the trial. Over the years of follow-up, scores declined by 3.15 units less in the Vitamin E group compared with the placebo group. In the memantine group, the scores declined 1.98 units less than the decline in the placebo group. Compared to the placebo group, those taking Vitamin E had an average delay in clinical progression of 19% per year, or approximately 6.2 months over the follow-up period. Patients receiving the vitamin also needed less caregiver assistance in comparison with the placebo group. There was no significant difference in all-cause mortality or safety issues reported between the placebo and Vitamin E groups. This study showed that high dose Vitamin E appears to slow functional decline and caregiver burden in patients with mild to moderate Alzheimer’s Disease. Maurice W. Dysken, MD et al. Effect of Vitamin E and Memantine on Functional Decline in Alzheimer Disease: The TEAM-AD VA Cooperative Randomized Trial JAMA. 2014;311(1):33-44. Source: USANA Health Sciences Essentials of Health

Extend the Healthspan

Multivitamins are not miracles… but they are important. This week’s (December 16, 2013) headlines stated that adults should stop taking multivitamin/mineral supplements (MVM) as they have no apparent health benefit and may potentially be harmful. We at the Linus Pauling Institute believe that these conclusions are wrong and ignore the totality of the evidence from decades of nutrition research.

Vitamins and minerals are needed by the body to maintain normal cell function, metabolism, and growth. If we don’t get enough of these essential nutrients, normal functioning of the body is impaired and health declines. Current evidence from the National Health and Nutrition Examination Survey (NHANES) shows that the large majority of the US population falls short of getting the recommended levels of many vitamins and minerals from their diet. For example, more than 90% of US adults do not meet the recommendations for vitamins D and E; 50-60% do not meet the recommendations for vitamin A, calcium, and magnesium; and more than 40% do not consume enough vitamin C. To be clear, these recommended levels of vitamins and minerals are the minimum amounts that nutrition research has found necessary to maintain good health. But there is some good news: there is support that people consuming a daily MVM containing the recommended amounts of most vitamins and minerals can fill these nutritional gaps safely, conveniently and at very low cost – less than a nickel a day. Heart illlustration filled with vegetabls, logo of DOH Conference. In addition to supporting normal body function, vitamins and minerals also may play a role in chronic disease prevention. For example, the largest and longest clinical trial of MVMs conducted to date, the Physicians’ Health Study II (PHS II), found a significant reduction in total cancer incidence in male physicians 50 years and older, excluding prostate cancer. Although the declines were not large, if every adult in the US took an MVM it could possibly prevent up to 130,000 cases of cancer each year. The PHS II also found a significant reduction in the incidence of cataracts. These findings of PHS II are consistent with those of several other clinical trials and are even more impressive given the fact that conventional clinical trial designs are biased against showing health benefits of essential nutrients. Therefore, taking a daily MVM supplement will not only help fill the known nutritional gaps in the average American diet, thereby assuring normal biological function and metabolism and supporting good health, but may also have the added benefit of reducing cancer and cataract risk (a bonus!) – which no existing pharmaceutical drug can do! To say the ‘case is closed’ and label MVM supplements as useless, harmful, or wasteful is non-scientific and does not serve public health.